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Fifth and the most complex way to approach it would be as a surrealistic expression of an artist working at the height of his powers and desperate to make the most of the final few opportunities left with him.

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Sign In. Keep track of everything you watch; tell your friends. Full Cast and Crew. Release Dates. Official Sites.

Company Credits. Technical Specs. Plot Summary. Plot Keywords. Parents Guide. External Sites. User Reviews.

User Ratings. External Reviews. Metacritic Reviews. Photo Gallery. Trailers and Videos. Crazy Credits. Alternate Versions. In pancreatitis, enzymes of the exocrine pancreas damage the structure and tissue of the pancreas.

Detection of some of these enzymes, such as amylase and lipase in the blood, along with symptoms and findings on medical imaging such as ultrasound or a CT scan , are often used to indicate that a person has pancreatitis.

Pancreatitis is often managed medically with pain reliefs , and monitoring to prevent or manage shock, and management of any identified underlying causes.

This may include removal of gallstones, lowering of blood triglyceride or glucose levels, the use of corticosteroids for autoimmune pancreatitis , and the cessation of any medication triggers.

Chronic pancreatitis refers to the development of pancreatitis over time. It shares many similar causes, with the most common being chronic alcohol use, with other causes including recurrent acute episodes and cystic fibrosis.

Abdominal pain, characteristically relieved by sitting forward or drinking alcohol, is the most common symptom.

When the digestive function of the pancreas is severely affected, this may lead to problems with fat digestion and the development of steatorrhoea ; when the endocrine function is affected, this may lead to diabetes.

Chronic pancreatitis is investigated in a similar way to acute pancreatitis. In addition to management of pain and nausea, and management of any identified causes which may include alcohol cessation , because of the digestive role of the pancreas, enzyme replacement may be needed to prevent malabsorption.

Pancreatic cancers , particularly the most common type, pancreatic adenocarcinoma , remain very difficult to treat, and are mostly diagnosed only at a stage that is too late for surgery, which is the only curative treatment.

Pancreatic cancer is rare in those younger than 40, and the median age of diagnosis is Pancreatic adenocarcinoma is the most common form of pancreatic cancer, and is cancer arising from the exocrine digestive part of the pancreas.

Most occur in the head of the pancreas. Jaundice occurs when the outflow of bile is blocked by the cancer. Other less common symptoms include nausea, vomiting, pancreatitis, diabetes or recurrent venous thrombosis.

An endoscopic ultrasound may be used if a tumour is being considered for surgical removal, and biopsy guided by ERCP or ultrasound can be used to confirm an uncertain diagnosis.

Because of the late development of symptoms, most cancer presents at an advanced stage. This may include management of itch , a choledochojejunostomy or the insertion of stents with ERCP to facilitate the drainage of bile, and medications to help control pain.

There are several types of pancreatic cancer, involving both the endocrine and exocrine tissue. The many types of pancreatic endocrine tumors are all uncommon or rare, and have varied outlooks.

However the incidence of these cancers has been rising sharply; it is not clear to what extent this reflects increased detection, especially through medical imaging , of tumors that would be very slow to develop.

Insulinomas largely benign and gastrinomas are the most common types. A solid pseudopapillary tumour is a low-grade malignant tumour of the pancreas of papillary architecture that typically afflicts young women.

Diabetes mellitus type 1 is a chronic autoimmune disease in which the immune system attacks the insulin-secreting beta cells of the pancreas.

As an untreated chronic condition, complications including accelerated vascular disease , diabetic retinopathy , kidney disease and neuropathy can result.

Diabetes mellitus type 2 is the most common form of diabetes. It is possible for one to live without a pancreas, provided that the person takes insulin for proper regulation of blood glucose concentration and pancreatic enzyme supplements to aid digestion.

The pancreas was first identified by Herophilus — BC , a Greek anatomist and surgeon. It was only in when Oskar Minkowski discovered that removing the pancreas from a dog caused it to become diabetic.

The way the tissue of the pancreas has been viewed has also changed. Now, immunohistochemistry can be used to more easily differentiate cell types.

This involves visible antibodies to the products of certain cell types, and helps identify with greater ease cell types such as alpha and beta cells.

Pancreatic tissue is present in all vertebrates , but its precise form and arrangement varies widely. There may be up to three separate pancreases, two of which arise from ventral buds, and the other dorsally.

In most species including humans , these "fuse" in the adult, but there are several exceptions. Even when a single pancreas is present, two or three pancreatic ducts may persist, each draining separately into the duodenum or equivalent part of the foregut.

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1 Comments

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